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AMA #18: Deep Dive: Sugar And Sugar Substitutes | The Drive with Peter Attia #141

Key Takeaways

  • All sugars are not created equal
  • “Is glucose a sugar? Yes. Is fructose a sugar? Yes. Are they the same? Not even close.” – Peter Attia
  • Glucose & fructose have dramatically different metabolic effects
  • Fructose doesn’t stimulate insulin secretion the way glucose does but that doesn’t mean it’s healthy

Introduction

In this special episode of The Drive, Peter Attia sits down with Head of Research at Attia Medical, PC Bob Kaplan (@bobkaplan), to take a deep dive into sugar consumption, the different types of sugar substitutes, and the difference between added sugar versus naturally occurring sugar. Note, this is only a preview. The full episode is only available to subscribers.

Host: Peter Attia (@PeterAttiaMD)

All Sugars Are Not Created Equal

  • A properly adherent food label will list “sugar” and “added sugar” separately
  • All sugars are not created equal: glucose, galactose, fructose, sucrose, allulose are all sugars but it’s not helpful to lump them into one category when evaluating
  • Glucose and fructose are monomers (form simplest building blocks of carbohydrates) – they have the same chemical formula but attached differently
  • “Is glucose a sugar? Yes. Is fructose a sugar? Yes. Are they the same? Not even close.” – Peter Attia
  • Glucose & fructose have dramatically different metabolic effects
  • When starch is broken down, it often ends up as glucose
  • Fructose doesn’t stimulate insulin secretion the way glucose does but that doesn’t mean it’s healthy
  • High fructose corn syrup was the dominant sweetener in the 80s and 90s
  • Sucrose is what happens when you take one molecule of glucose and bond it with one molecule of fructose
  • Sucrose is white granulated, refined sugar
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Notes By Maryann

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