Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an assistant professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a senior research scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast. Dom focuses

Dr. Rhonda Patrick speaks with Dr. Satchin Panda, a professor at the Salk Institute for Biological Studies in La Jolla California. Satchin's work deals specifically with the timing of food and it's relationship with our biological clocks governed by circadian rhythm and also the circadian rhythm in general. In this video we discuss... The fascinating

Ryan Holiday (@RyanHoliday) is a strategist and writer. He dropped out of college at 19 to apprentice under Robert Greene, author of The 48 Laws of Power, and later served as the director of marketing for American Apparel. His company, Brass Check, has advised clients like Google, TASER, and Complex, as well as many prominent

Kevin is Senior Maverick at Wired Magazine, which he co-founded in 1993. He also co-founded the All Species Foundation, a non-profit aimed at cataloging and identifying every living species on earth. In his spare time, he writes bestselling books, co-founded The Rosetta Project, which is building an archive of all documented human languages, and serves

Marc Andreessen (@pmarca) is a legendary figure in Silicon Valley — and worldwide. Even in the epicenter of tech, it’s hard to find a more fascinating icon. Marc co-created the highly influential Mosaic Internet browser, the first widely used graphical web browser. He also co-founded Netscape, which later sold to AOL for $4.2 billion. Then he

Dr. Rhonda Patrick speaks with Ray Cronise, a former NASA material scientist and cofounder of zero gravity, a company that offers weightless parabolic flights to consumers and researchers. In this episode, coming at the tail end of a rather extreme 23-day water fast for Ray, we discuss, perhaps unsurprisingly, some of the benefits that are

Seth Godin (@thisissethsblog) is the author of 17 bestselling books that have been translated into more than 35 languages. He writes about the way ideas spread, marketing, strategic quitting, leadership, and — most of all — challenging the status quo in all areas. His books include Linchpin, Tribes, The Dip, Purple Cow, and What to

Dr. Rhonda Patrick returns with another nutrient dense discussion with Joe on cryotherapy/cold showers, diet, and exercise. As always this is not to be missed and we've noted all the most important parts for you, as it can be overwhelming in detail.

“F*ck it… I’m just not going to play this traditionally anymore.” – Chris Sacca Chris Sacca was recently the cover story of the “Midas Issue” of Forbes Magazine. The reason: He is a newly-minted billionaire and the proprietor of what will likely be the most successful venture capital fund in history: LOWERCASE I of LOWERCASE Capital. He’s an early-stage

Sometimes one interview just isn’t enough. That was certainly the case with Tim's good friend, Chris Sacca. Chris (who he interviewed before) was recently the cover story of the Midas Issue of Forbes magazine. He was on the cover because he’s a newly minted billionaire and the proprietor of what will likely be the most

LONGEVITY, EPIGENETICS, MICROBIOME HEALTH & THE DIFFERENCE BETWEEN EATING FOR LONG-TERM WELLNESS VERSUS PERFORMANCE This episode is a geeky deep dive into the hardcore science behind everything from telomeres and the mechanisms behind aging and longevity to the primacy of maintaining microbiome health; oxidative stress and the relationship between inflammation and chronic disease; epigenetics and genetic

Usually, it’s Tim's job to deconstruct world-class performers. This time around, the tables are turned. Many of you have asked to hear Tim interviewed, so this week Daymond John (@thesharkdaymond), star of ABC’s Shark Tank and CEO and founder of FUBU, is in charge and asking the questions. Daymond has a new book called The

Incredible interview with the one and only Quentin Tarantino. Learn about his favorite 80's movies, his writing method, and just enjoy an interview with a true movie lover.

By popular demand, this is a follow-up with the amazing Derek Sivers (@sivers)! This episode can be listened to independently of Tim's first popular conversation, and he answers some of my (and your) favorite questions. Originally a professional musician and circus clown, Derek created CD Baby in 1998. It became the largest seller of independent music online,

Tim looks back at his amazing year in podcasting and highlights the best ideas/recommendations.