#1589 – Dr. Mark Gordon & Andrew Marr | The Joe Rogan Experience

Key Takeaways

  • Diet has a significant impact on one’s emotional state
  • Inflammation increases signs of depression, insomnia, mood swing, brain fog
  • When the brain has inflammation, it changes the chemistry which disrupts all control mechanisms – function and ability to sequence is gone
  • Cytokines get into the brain and cause psychiatric problems related to post-COVID recovery – depression, lethargy, low energy
  • Recommended supplements and dosing for bulletproofing: Zinc (15-30mg twice/day), Quercetin (500mg twice/day), vitamin D – dose depends on blood test results, DHEA (take at night)

Introduction

Dr. Mark Gordon (@MarkLGordon) is an expert in the field of neuroregenerative medicine and the treatment of Traumatic Brain Injuries. He is a strong advocate of Functional Medicine and promoting wellness by correcting underlying symptoms. Dr. Gordon was key in recognizing Traumatic Brain Injury as a hormonal deficiency and taking a functional approach to treatment.

Special Forces Green Beret Andrew Marr is co-founder of the Warrior Angels Foundation, and author of Tales From The Blast Factory.

In this episode Joe Rogan sits down with Dr. Mark Gordon and Andrew Marr to discuss nutrition, supplementation and the damaging effects of inflammation.

Host: Joe Rogan (@joerogan)

Importance Of Eating Whole Foods

  • Foods rich in curcumin and turmeric are protective against inflammation
  • Hardening of the arteries is not cholesterol – it’s calcium hardening on the walls of the arteries to fix damage caused by lifestyle (e.g., smoking, poor diet)
  • Our soils are depleted of nutrients that used to be present
  • Stay away from GMOs because it’s harder for the body to breakdown
  • We have increasing numbers of people with gluten sensitivity
  • Vitamin C helps with immune system – but you can get the same results through diet by eating citrus fruit

Nutrition And Emotional State

  • Diet has a significant impact on one’s emotional state
  • In patients with ADD, high inflammatory nutrition makes it worse
  • Inflammation increases signs of depression, insomnia, mood swing, brain fog
  • People with a low carb, keto, carnivore diet often report improvements in mood
  • Gut inflammation creates depression

COVID-19 Cytokines

  • COVID-19 causes spike in immune system production of cytokines
  • Vitamin D stimulates the immune system and protects the body from inflammatory cytokines
  • Cytokines cause inflammatory pathway to disrupt chemicals in the brain
  • Cytokines get into the brain and cause psychiatric problems related to post-COVID recovery – depression, lethargy, low energy
  • When the brain has inflammation, it changes the chemistry which disrupts all control mechanisms – function and ability to sequence is gone
  • COVID-19 survivors must get tested for inflammation markers and address to avoid adverse mental health outcomes

COVID-19 & Proper Supplementation  

  • You don’t just want to take one vitamin, you want to create a whole balanced ecosystem
  • Zinc & quercetin increase energy production and is protective against the virus
  • Quercetin has a nootropic effect, decreases inflammation in the brain, increases cognitive ability, and increases mitochondria which produce energy
  • Testosterone stimulates immune systems that defend against infection and viral bacteria, improving innate immunity
  • Vitamin D draws calcium and phosphate from the gut
  • DHEA is an immune stimulator, important in protecting the heart, stimulates growth hormone, reduces inflammation markers
  • Glutathione is key anti-inflammatory support in the brain but it gets absorbed quickly in the brain
  • Look for multi-vitamin with ascorbyl palmitate such as ultra-nutrient by pure encapsulations
  • Recommended supplements and dosing: Zinc (15-30mg twice/day), Quercetin (500mg twice/day), vitamin D – dose depends on blood test results, DHEA (take at night)
  • Also recommended for brain health: Omega-3 by  Nordic Natural or this one by Thorne

Functional Medicine Approach To Traumatic Brain Injury (TBI)

  • Andrew Marr was experiencing trauma from his time in the special forces
  • Post-service, Marr experienced extreme brain fog, mood swings, anger – to the point that suicide seemed like the best way out
  • Special operations division commits suicide at a higher rate than others
  • Current treatment for TBI is still just psychotropic medication and talk therapy but the majority of people do not get therapeutic benefit
  • When Dr. Mark Gordon and Andrew Marr worked together, he introduced a functional approach: lab tests, identifying neuroinflammation, looking for deficiencies – and the turnaround was almost instant
  • Neuroinflammation isn’t the only cause but is a major contributing factor
  • Neuroinflammation can be caused by the environment, poor diet, medication, lack of sun, water quality
  • Next steps: hope is to use this approach and spread beyond veterans to current and former athletes, non-athletes with symptoms, homeless, incarcerated
  • Clinical depression rates: 1 out of 5 adults; 50% of 13-18 year olds

Non-Pharmaceutical Treatments of TBI

  • Additional therapies work but the underlying inflammation must be addressed first
  • Hyperbaric oxygen therapy – but needs to be maintained for results (i.e., can’t stop it)
  • It’s possible that the combination of functional medicine approach plus hyperbaric oxygen therapy could be the accelerator
  • Electric stimulation of the brain is possible, but again – inflammation must be addressed
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Notes By Maryann

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