The Joe Rogan Experience | The Most Popular Podcast Notes of All-Time

11) The Joe Rogan Experience #1169 – Elon Musk

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Key Takeaways

  • It will be very tempting to use AI as a weapon (and it will probably happen)
  • “A company is essentially a cybernetic collective, of people and machines”
    • Google, plus all the humans that use it, are one giant cybernetic collective
      • We’re all effectively programming their AI – This is also true of Facebook, Instagram, Twitter, etc.
  • Elon was once a big proponent of slowing down AI development and regulating it more heavilythis is talked about in the book, Life 3.0
  • The scenario in which we merge with AI is the one that probably turns out best for us
    • “If you can’t beat it, join it”
  • “Your phone is already an extension of you. You’re already a cyborg, and most people don’t realize it.”
    • But – The communication rate between you and your phone/computer is very slow (compared to what it could be) – this is the problem Neuralink is setting out to solve
  • “I think a Tesla is the most fun thing you could possibly ever buy”
    • “It’s not a car, it’s a thing to maximize enjoyment”
  • I don’t think you’d necessarily want to be me. I don’t think people would like it that much.”
    • Elon says the worst part about “being him” – “It’s very hard to turn it off”
  • “Give people the benefit of the doubt. Assume they’re good until proven otherwise. Most people are pretty good people.”
    • “This may sound corny, but love is the answer”
    • “It wouldn’t hurt to have more love in the world

 

10) The Joe Rogan Experience #1235 – Ben Greenfield

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Key Takeaways

  • The carnivore diet is really like an elimination diet
    • Perhaps the benefits people experience are the result of eliminating much of what causes them issues and aren’t solely from eating meat
  • Marijuana seems to lower testosterone temporarily
  • Tetrahydrocannabinol (THC), the main psychoactive ingredient in marijuana, seems to act on a lot of mTOR pathways in the body (it inhibits them)
  • “The skin is a mouth” – it readily absorbs what you put on it
  • Get a 23andMe DNA test – it will give you a TON of useful information
  • Lectins can cause certain people to have inflammatory responses to vegetables 
  • Try natural/man-made remedies before trying supplements
  • We have photoreceptors on our skin (this is why you should still make the room you’re sleeping in fully dark, even if you’re wearing a sleep mask)
    • To reset your internal clock when traveling – Use light, food, and movement
  • CBD can enhance the amount of time you spend in deep sleep 
  • THC decreases sleep latency (how long it takes you to fall asleep) but reduces the amount of time you spend in deep sleep
  • Glympthatic system activity is increased when we sleep on our sides

 

9) The Joe Rogan Experience #568 – Dr. Rhonda Patrick

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Key Takeaways

  • People with TBI (traumatic brain injury) can often have Alzheimer’s-like symptoms at much younger ages and are much more likely to have developed Alzheimer’s later on (e.g. NFL, MMA, etc.)
    • Risk even higher with APOE4 genetic risk factors
  • The biggest risk factor for developing Alzheimer’s Disease? – Whether or not you have any copies of the ApoE4 gene (a 23andme will allow you to see your ApoE4 genotype)
  • Diet: Focus on what you SHOULD eat instead of what you SHOULDN’T
    • Aim to eat a diet rich in micronutrients
    • Eat more fiber and probiotics
      • Recommended probiotic: VSL#3 (others are likely not effective)
    • Try to eat more turmeric as it’s a great source of glutathione
    • Avoid sugar and refined crap
  • Supplements:
  • Genetic predisposition + bad diet + lack of exercise + stressful environment = Disaster

 

8) The Joe Rogan Experience #773 – Dr. Rhonda Patrick  

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Key Takeaways

  • Cold Showers and high-intensity workouts increase norepinephrine in the brain
  • Aerobic exercise increases brain-derived neurotrophic factor
  • Starting at age 40, people begin to lose muscle mass (and it’s much harder to gain as you get older)
  • Consume more garlic and curcumin
  • What you eat impacts your body in such profound ways – most don’t realize this
  • EAT MORE WHOLE FOODS
  • Fresh fruit is a great dessert – you don’t need to have cake/pie

 

7) The Joe Rogan Experience #1121 – Michael Pollan

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Key Takeaways

  • It’s important to remember psychedelics aren’t for everybody
  • Psychedelics are not addictive and aren’t drugs of abuse – they’re probably even anti-addictive
  • “Most bad trips are the result of someone resisting what is happening” – Their ego is dissolving, and they try to stop it
    • The best thing to do – “Surrender, trust, and let go”
  • Everything you see in a psychedelic experience is really in your mind – everything you see comes from real psychological facts originating from your unconscious
    • “LSD is an unspecific amplifier of mental activity”
  • “Mental health treatment in this country is just a mess”
    • If you compare it to any other branch of medicine, it’s accomplished very little
  • Depression is the largest cause of disability worldwide 

 

6) The Joe Rogan Experience #1108 – Peter Attia

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Key Takeaways

  • Peter will very often only eat one meal a day. What does he eat? – It’s usually a 3,000 calorie meal consisting of:
    • A huge salad – Romaine lettuce, tomatoes, mushrooms, cucumbers, carrots, EVOO, freshly squeezed lemon, salt, and pepper
    • A serving of protein – he cycles through salmon, pork, steak, or game meat
    • A starchy vegetable – potatoes or rice
  • The only things to increase lifespan across all model organisms (yeast, worms, flies, mammals) are:
    • Caloric/dietary restriction
    • Rapamycin (it’s a drug) – Peter believes we’ll all be taking it one day
      • Rapamycin inhibits mTOR (fasting also does the same thing)
  • When it comes to lifting weights, Peter says you can lift heavy every day if you’re willing to do away with the negative motion (shortening the muscle)
    • This is equivalent to doing deadlifts but dropping the weight instead of slowly lowering it
  • “Your body can’t tell the difference between a glass of orange juice and Coca-Cola”

 

5) The Joe Rogan Experience #1054 – Dr. Rhonda Patrick  

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Key Takeaways

  • Just like people have adverse reactions to certain foods, people will certainly have adverse reactions to vaccines
  • Once you hit 25, your aerobic capacity decreases 10% per decade (or 1% per year)
    • One study had a group do 24 high-intensity interval cycling classes within 8 weeks – at the end of the 8 weeks, average VO2 max had improved 12%
  • On Refined Sugar:
    • Almost EVERYTHING has sugar in it – if you go into a grocery store and pick up a random item, more likely than not it’ll contain sugar
    • Refined sugar has been shown to increase inflammatory biomarkers and small dense LDL particle number (which is bad)
    • There isn’tt that much difference between drinking a large glass of orange juice and a large glass of soda
    • Refined sugar decreases testosterone
    • The easiest thing you could do to have the biggest impact on their health would be to cut out refined sugar
  • A low folate diet causes DNA damage
    • One good source of folate – leafy greens.
  • Lutein, found in high amounts in kale, increases learning ability and memory
  • “The gut is so important. It’s the major source of inflammation in the body.”

 

4) The Joe Rogan Experience #1178 – Dr. Rhonda Patrick

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Key Takeaways

  • The carnivore diet seems to improve autoimmune disorders. Why?
    • It mimics calorie restriction and fasting
    • The diet replenishes the immune system through apoptosis
    • It produces changes in the microbiome
  • Dr. Patrick has many concerns about the carnivore diet
    • People on the diet are most likely not getting the micronutrients they need (like vitamin E, vitamin C, and folate)
    • “At the end of the day, there’s no data” – Going on a carnivore diet may be harmful long term
    • By not eating vegetables, you’re missing out on key fiber that the gut needs
  • Genetics determine if you are likely to experience a placebo effect
  • Fish oil (Rhonda recommends this brand) increases dopamine in the prefrontal cortex
  • Sleep is one of the ways you clear away amyloid plaques (which develop and cause dementia) in the brain
    • During sleep, you squirt cerebral spinal fluid into the brain which clears out the plaques and other junk
  • Rhonda loves this ketone ester from HVMN
    • When taking it, she experiences a decrease in anxiety (it got her to a blood ketone level of about 4.5 mmol in about an hour) and a feeling of “being present”
  • We all need to up our sulforaphane intake (found in broccoli and brussel sprouts)
  • Even a single sauna session has been found to improve depressive symptoms

 

3) The Joe Rogan Experience #1309 – Naval Ravikant

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Key Takeaways

  • When you combine things you’re not supposed to combine, people get interested
  • Don’t read to finish books. Read to satisfy your intellectual curiosity.
  • EVERYBODY on Earth can be wealthy
  • Everybody wants to be wealthy, everybody wants to be happy, and everybody wants to be fit
    • Here’s the good news – all 3 of those things can be taught
  • Happiness is a choice
  • “Desire is suffering… every desire you have is an axis where you will suffer. So just don’t focus on more than one desire to time. The universe is rigged in such a way that if you just want one thing, and you focus on that, you’ll get it, but everything else you gotta let go.”
  • If you want to operate at peak performance, you need a calm mind
  • We live in an age of infinite leverage, and because of that, the impacts of good decision-making are much higher than they used to be
  • Knowledge workers function like athletes – they train, sprint, then rest and reassess
  • The information revolution, by making it easier to communicate, connect, and cooperate, is allowing us to go back to working for ourselves
  • We need a culture of continuous adult education
  • Society will always create new jobs, but it’s impossible to predict what those jobs will be
    • “I do believe that automation, over a long enough period of time, will replace every non-creative job”
  • There are MANY problems with Universal Basic Income
  • You won’t see General AI anytime soon
  • Naval practices the “art of doing nothing” meditation, here’s how you do it:
    • “Sit down, close your eyes, get in a comfortable position, and whatever happens, happens. If you think, you think. If you don’t think, you don’t think. Don’t put any effort into it.”
  • Protect your time like it’s all you have
    • You’ll have to ruthlessly decline meetings if you want to do anything of importance in this world
  • Find the thing that looks like work to others, but feels like play to you, and then go all-in on it

 

2) The Joe Rogan Experience #1234 – David Sinclair, Ph.D.

Key Takeaways

  • Sirtuins are genes which protect all organisms from deterioration and disease
  • NMN and resveratrol are molecules which essentially mimic the effects of the sirtuin genes
    • “You can think of resveratrol as the accelerator pedal for the sirtuin genes, and NMN as the fuel”
    • NMN also boosts NAD levels (which sirtuins need to function)
  • “Aging should absolutely be classified as a disease”
    • Why isn’t it? – Because it happens to everybody – “It’s only because we all tend to go through this that we think it’s acceptable”
  • One of the best things you can do to increase your chances of living longer – don’t overeat
  • X-rays damage the epigenome

Read the full notes here

 

1) The Joe Rogan Experience #1109 – Sleep Expert and Neuroscientist Dr. Matthew Walker

Read the full notes here

Key Takeaways  

  • One half of your brain won’t sleep as deeply as the other when sleeping in a foreign environment such as a hotel room
  • “Sleep is the greatest legal performance-enhancing drug that most people are probably neglecting”
  • One hour of iPhone use before bed will delay the onset of melatonin production by about 3 hours (your peak melatonin levels will also be about 50% less)
  • Your brain needs to drop its temperature 2-3 °F in order to sleep (so keep your room as cold as you can tolerate)
  • Men who sleep 5-6 hours a night will have a level of testosterone 6-10 years their senior
  • Humans beings are the only species that deprive themselves of sleep for no apparent gain. Mother nature has never faced the challenge of coming up with a safety net for lack of sleep.
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