The Kevin Rose Show – Dr. Andrew Weil on Medicinal Mushrooms, Microdosing, Tea, and Supplements

Check out The Kevin Rose Show Episode Page & Show Notes

Key Takeaways

  • When oil starts to smoke, it’s actually a “toxic cloud” that you don’t want to breathe in
  • Matcha is ground very fine, making it prone to oxidation – so it’s very important that it’s stored correctly
    • If it’s exposed to air, it loses the vibrant green color (it becomes yellowish), and loses some of its flavor
    • “Many people have never tried quality matcha. They’ve only had the inferior stuff.”
  • It’s a good idea to eat as many different color vegetables as you can
  • When you supplement with turmeric/curcumin, you need to take it with black pepper if you want it get out of the gastrointestinal (GI) tract
  • Iceland has the lowest worldwide incidence of depression
    • Coincidentally, they also have the highest serum omega-3 levels in the world

Products and Supplements Mentioned

  • Andrew really likes cooking with Thrive Algae Oil due to its healthiness, and high smoke point
  • Lion’s mane mushrooms have a unique nerve growth factor in them, that’s beneficial for the nervous system
  • “One big group of mushrooms that are very beneficial are the polypores
    • A lot of them have immune enhancing properties
    • Examples – reishi and turkey tail mushrooms
    • You can buy polypore liquid extracts
  • What does Andrew supplement with daily?
  • Cordyceps mushrooms are good for increasing energy
  • Reishi mushrooms have a very significant anti-inflammatory effect
  • What type of matcha tea would Andrew recommend for a first time matcha drinker?
  • L-Theanine is an amino acid, which you can buy as a supplement, commonly found in green tea
    • It produces a state of relaxation/calm
    • In combination with caffeine (like in matcha tea) – it produces a state of alert relaxation
  • Curcumin is a compound in turmeric which has very good anti-inflammatory properties
  • Dr. Weil also recommends eating lots of fermented foods
    • He ferments his own sauerkraut, pickles, kimchi, and radishes with the Perfect Pickler
  • Kevin recently supplemented with magnesium during a 5 day water-only fast
  • Andrew has been microdosing with 100 mg of psilocybin containing mushrooms (aka magic mushrooms)
    • “I find it interesting and useful”
    • He doses 1-2 times a week
    • The biggest thing he’s noticed – it’s had a positive effect on his mood
  • A few supplements/foods which can help lower blood glucose levels:
  • An NSAID (Nonsteroidal Anti-Inflammatory Drug) alternative that Dr. Weil recommends – Reishi mushrooms

Books Mentioned

Intro

Hydrogenated Oils

  • AKA Trans fats
    • Hydrogenation is a process in which a liquid unsaturated fat is turned into a solid fat by adding hydrogen
    • During this manufactured partially hydrogenated processing, a type of fat called trans fat is made
  • “When you change the chemistry of fatty acids, you often increase their toxicity and especially their carcinogenicity”
    • Artificially hydrogenated fats are a huge cause of atherosclerosis and heart disease
  • People used to think polyunsaturated oils (sesame oil, corn oil, canola oil) were good for heart health – this is NOT the case
    • “Those polyunsaturated oils are very chemically unstable”
    • If they’re exposed to heat and oxygen, or light, they break down and form pro-inflammatory carcinogenic compounds

More About Oils

  • What oils does Andrew consume?
    • Primary olive oil
    • Some monounsaturated fats
      • He really likes Thrive Algae Oil
        • It has a very very high smoke point, and a neutral taste
    • He uses some flavored oils like toasted sesame oil, walnut oil, hazelnut oil 
      • “I use them moderately, and make sure I don’t heat them”
  • A PSA
    • When oil starts to smoke, it’s actually a “toxic cloud” that you don’t want to breathe in
  • Can you heat olive oil?
    • Dr. Weil says recent research shows it’s fine, just don’t get near the smoke point (so it’s okay to saute with)

Mushrooms

  • Andrew wrote the foreword for Psilocybin Mushrooms of the World: An Identification Guide
  • Kevin has been trying lion’s mane mushrooms, bought from the grocery store
    • He cuts them up, and sautes with them olive oil
    • Andrew says lion’s mane mushrooms have a unique nerve growth factor in them, that’s beneficial for the nervous system
      • He has seen good results in people with peripheral neuropathy and various kinds of brain problems
      • Many people report increased memory after consuming them
      • It may also protect against dementia
    • You can buy lion’s mane mushroom capsules
  • “One big group of mushrooms that are very beneficial are the polypores
    • These are fungi that grow on both living and dead trees in forests
    • They’re all non-toxic, but some are inedible due to their “woodiness” or bitterness
    • But some are edible – Like reishi or turkey tail
    • A lot of them have immune enhancing properties
    • You can buy polypore liquid extracts 
  • What does Andrew supplement with daily?

How to Know if a Wild Mushroom is Toxic

  • “You learn mushrooms the same way you learn people – by spending time with them, and learning to recognize them”
    • So Andrew recommends going out foraging for mushrooms with people who know a lot about them
  • “The best way to learn about mushrooms is from people who know them. It’s much harder to learn about them from books.”
  • Rule #1 – Be able to identify mushrooms that can kill you (there aren’t very many)

Mushrooms for Different Purposes

Matcha Tea

  • Andrew first discovered matcha tea when he was 17 in Japan, back in 1954
    • At this time, you couldn’t buy it in the U.S.
  • With matcha tea, uniquely, you’re consuming the entire leaf
    • The leaves for matcha are grown in a special way – they’re heavily shaded for a few weeks before harvest, and because of this, the leaves become bigger/thinner and produce more chlorophyll, l-theanine, and flavoring agents
  • Matcha is also ground very finely, making it prone to oxidation – so it’s very important that it’s stored correctly
    • If it’s exposed to air, it loses the vibrant green color (it becomes yellowish), and loses some of its flavor
    • “Many people have never tried quality matcha. They’ve only had the inferior stuff.”
  • Because he’s such a fan of matcha, and wanted to make it more widely available, Andrew started the company Matcha Kari
    • Kevin is an investor
    • The matcha they import comes Uji, Japan – which is near Kyoto
    • What type of matcha would Andrew recommend for a first time matcha drinker?
  • Andrew is a fan of iced matcha
    • To make it, he mixes room temperature water, with 3 scoops of matcha, and then he uses an electric whisk to whisk it up quickly, and lastly adds ice cubs (he drinks it unsweetened)

More About Tea

  • L-Theanine is an amino acid, which you can buy as a supplement, commonly found in green tea
    • It produces a state of relaxation/calmness
    • In combination with caffeine (like in matcha) – it produces a state of alert relaxation
      • “You’re alert, but calm and focused”
  • Other health benefits of tea
    • Research out of Japan has shown that drinking 4-5 cups of green tea per day was associated with lower all cause mortality
    • Other studies show tea drinking lowers cardiovascular disease risk
      • The benefits are contributed mostly to the antioxidant content of the green tea (but there are also antioxidants in coffee, chocolate, fruits, vegetables etc.)

Why You Should Eat Across The Color Spectrum

  • Plants contain phytonutrients – These are compounds found in plants believed to be beneficial to human health
    • Many of these are pigments, and each color is associated with different protective effects
      • For this reason, it’s a good idea to eat as many different color vegetables as you can
    • You want to get as many different kinds of plant phytonutrients into your diet as possible
      • “The way to do that is to eat a great variety of fruits, vegetables, herbs, spices – all of these have unique compounds in them”

Can you just supplement, instead of eating vegetables?

  • “While I think there is a role for taking dietary supplements and vitamins, I don’t think that taking these things in supplement form produces the same benefits as eating whole foods found in nature. At best, they are partial representations of the complexes that nature produces.”
  • So it’s best to use supplements as insurance
  • Andrew says there are also synergistic effects of the beneficial compounds found in plants – so isolating one compound and taking it as a supplement, won’t be as effective
    • Example – Many years ago it was found that carotenoid pigments had a protective effect against lung cancer
      • People (mostly smokers) went on to take beta-carotene as a supplement, but it turns out that isolated beta-carotene actually increases the risk of lung cancer
      • Instead – just eat the vegetables that have carotenoid pigments in them (carrots, and other yellow/red vegetables)
        • This way, you’re getting all the carotene compounds (alpha-carotene, beta carotene, lutein, zeaxanthin, AND beta-carotene)

Other Supplement Thoughts and Recommendations

  • Rapamycin – Peter Attia and Kevin Rose talked about it extensively in these Podcast Notes
    • Peter said he supplements with a low dose 
    • BUT Andrew says – “I would be very wary of taking a strong immunosuppressant like that”
  • Curcumin – a compound in turmeric which has very good anti-inflammatory properties
    • In these Podcast Notes Dr. Peter Attia recommended a certain formulation of curcumin, called Theracumin
    • India actually has the lowest rates of Alzheimer’s Disease in the world, and many think it’s because of their very high turmeric consumption
    • Note – if you don’t take curcumin with black pepper, it doesn’t get out of the GI tract
      • So it’s fine taking it without black pepper if you’re treating a GI issue, but if not, consume it with black pepper
    • Andrew takes Turmeric Strength for Whole Body by MegaFood (it has a black pepper extract in it)
    • People in Okinwa commonly drink a cold, unsweetened, fermented turmeric tea
  • Dr. Weil also recommends fermented foods
    • He ferments his own sauerkraut, pickles, kimchi, and radishes

Toxins

  • “I would bet that Parkinson’s Disease is going to be shown to be caused by environmental toxic effects”
  • There’s a disease similar to ALS in Guam that has been traced to consumption of a toxic compound in nuts
  • “It’s possible that many of these very serious neurodegenerative diseases are set off by environmental toxicity”

Omega-3s for Brain Health

  • “I think they’re crucial” – Specifically DHA
  • Most people are deficient in omega-3 fatty acids
  • Iceland has the lowest worldwide incidence of depression
    • Coincidentally, they also have the highest serum omega-3 levels in the world
      • They eat a ton of fish, as well as roasted seabirds that frequently eat fish
      • They also drink a lot of sheep milk, from sheep that graze on arctic grasses and plants, that have omega-3s in them

Dr Weil’s Thoughts on Dairy

  • He loves fermented milk products like Greek and Middle eastern yogurt
  • He also likes high-quality cheese
    • Research shows that the saturated fat in cheese may actually have a heart protective effect
    • Andrew prefers cheeses from high mountain areas in Europe (they have a better fatty acid profile) – like cheese from France and Italy
    • “Real cheese is actually a living culture of organisms”
      • “Most cheeses sold in supermarkets are dead. There’s no living organisms in them.”

Fasting

  • “I think there is very good evidence that intermittent fasting has a very beneficial effect on metabolism, and in particular, can help with regulation of blood glucose levels”
  • Longer term water-only fasts have been shown to put autoimmune diseases into total remission (like asthma, Rheumatoid arthritis, and ulcerative colitis)
    • Kevin recently supplemented with magnesium during a 5-day water-only fast

Microdosing

  • Andrew tried microdosing with LSD and wasn’t really a fan- “I didn’t like the energy it created in my body, and it lasted way too long”
    • Kevin also wasn’t a fan when he tried it – “It was like taking 3 cups of coffee, one after another. I didn’t get any creativity boost.”
      • He says he took 15-20 ug
  • Andrew has been microdosing with 100 mg of psilocybin containing mushrooms (aka magic mushrooms)
    • “I find it interesting and useful”
    • He doses 1-2 times a week
    • The biggest thing he’s noticed – it’s had a positive effect on his mood

More on Psychedelics

  • “Many people who have chronic illnesses, whether it’s chronic pain or autoimmune disease, if they can have the experience of having even a few hours without that condition, that’s motivation to find ways of making that happen more often”
    • Andrew had a friend with severe rheumatoid arthritis and after an experience with MDMA, he was in complete remission
  • Kevin recently did a high dose guided psilocybin session
  • Oregon is voting soon on whether or not to make psilocybin a prescribable compound
  • Andrew says he had a lifelong cat allergy that disappeared immediately after an LSD trip a while back

Controlling Blood Glucose Levels

  • Diabetes, pre-diabetes, metabolic syndrome, Alzheimer’s Disease and more, are all the result of sustained high levels of blood glucose/insulin
  • To help lower blood glucose levels, Andrew recommends a few things:
    • Exercise
    • Eat lower glycemic index foods (these don’t spike your blood sugar as much – vegetables, beans, protein)
    • Stop eating sugar and refined carbs
    • And a few supplements/foods that may help:
  • “Most cases of pre-diabetes or diabetes can be put into remission just with lifestyle changes”

Andrew’s Predictions for the Future

  • “Stem cell therapy is on the horizon”
    • “We’re very close to being able to regenerate spinal cords, to be able to heal pancreases, and repair areas of heart muscle damaged by heart attacks”
  • Individualized medicine 
    • In the future, you’ll be able to know which diet is right for you and why
    • Kevin is excited about the field of genetics and using your own data to customize your health

NSAIDs – Nonsteroidal Anti-Inflammatory Drugs

  • “NSAIDs are very useful drugs, but I don’t think they’re safe for long term use”
    • It’s a huge problem that they’re so widely available over the counter in various forms
    • They’re fine to take occasionally for general pain
    • But there are many risks taking them long term – particularly gastrointestinal (GI) bleeding
  • An NSAID alternative that Dr. Weil recommends – Reishi mushrooms

These notes were edited by RoRoPa Editing Services

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