Sleep – it’s important. You know it, I know it, we all know it. But sometimes, it’s not that easy. It’s hard for Type A personalities to wind down at the end of the night. What do the top performers use for help?Read More
Serge is a hardcore biohacker and serial entrepreneur. In this episode Kevin and Serge talk about Serge’s extreme daily regimen of compounds to biohack every aspect of his brain and body. Serge has studied at Cornell, worked at Google, and was youngest in his class at Stanford Business School. Do not try any of this at home.Read More
In this episode Tim focuses on a topic that has been a lifelong personal struggle for many people: sleep.
Tim has found that if you prioritize sleep — and recovery, in general — it magnifies everything else in your life, from your emotional health to physical training. To help you take better care of your mind and body, he’s gathered some of the best advice from multiple guests about rest and regeneration.
This episode includes tips and recommendations from:
Strength coach Charles Poliquin
Obstacle course racer Amelia Boone
Comedian Mike Birbiglia
Dr. Peter Attia
James Altucher sat down with Shawn Stevenson of the Model Health Show and author of “Sleep Smarter: 21 Essential Ways to Sleep Your Way to a Better Body, Better Health, and Bigger Success” to discuss all things health. Shawn himself used to be severely overweight. One day he decided he needed to get things into gear and completely changed how he was living. James and Shawn get into why we need to exercise, how we should eat, where our water should come from, and of course, why we all need more sleep.Read More
Dr. Ruth Patterson, a professor in the UC San Diego Department of Family Medicine and Public Health as well as Associate Director of Population Sciences and leader of the Cancer Prevention program at Moores Cancer Center at UC San Diego Health. If you enjoyed my last episode with Dr. Satchin Panda, I have good news! This will also be a great episode for you, since we talk about some similar ideas, but focus more on the human side of things, especially when it comes to time-restricted eating, since Dr. Patterson does primarily clinical research. In this 45-minute podcast, we talk about… The importance of time-restricted eating as a practical public health intervention, mostly for it’s ease of implementation, that may have a widespread impact on disease risk. Why you should probably make sure your time-restricted eating window occurs earlier in the day, rather than later. How the first 5% drop in weight loss can have disproportionately large effects on the metabolic factors associated with breast cancer risk when compared with subsequent weight loss. The association of longer fasting durations beginning earlier in the evening and improved sleep in humans, as well as spontaneous physical activity in their day-to-day lives. The relationship between metabolism and breast cancer risk. The effect of lifestyle factors, such as obesity, physical activity, what and even when you eat, whether or not you smoke tobacco… and how even modest changes, such as consuming food earlier in the day and only during an 11-hour window, can decrease breast cancer risk and recurrence by as much as 36%. The importance of starting your fast earlier in the evening, and how an earlier eating window has been shown to correlate to reductions in inflammatory markers.Read More
Dr. Rhonda Patrick speaks with Dr. Satchin Panda, a professor at the Salk Institute for Biological Studies in La Jolla California. Satchin’s work deals specifically with the timing of food and it’s relationship with our biological clocks governed by circadian rhythm and also the circadian rhythm in general. In this video we discuss… The fascinating history of experimentation that ultimately elucidated the location for the region of the brain necessary for a properly timed sleep-wake cycles. The relationship between our body’s “master clock” and it’s many peripheral clocks. Why infants sleep so intermittently, instead of resting for a longer, sustained duration like healthy young adults… and why this sustained rest also goes haywire in the elderly. The fascinating work Dr. Panda took part in that lead to the discovery of a specialized light receptor in the eye that sets circadian rhythms and is known as melanopsin. The important relationship between the relatively light insensitive melanopsin, which requires around 1,000 lux of light to be fully activated, and its control of the circadian clock by means of activation of the suprachiasmatic nucleus and suppression of melatonin. The effects light exposure seems to have on next-day cortisol, a glucocorticoid hormone that regulates around 10-20% of the human protein-encoding genome. The clever experimental design by which Dr. Panda and his colleagues discovered that certain circadian rhythms, especially of the liver, are entrained by when we eat, instead of how much light we get. This underlines the fact that, when managing are circadian rhythm, both elements are important! One of the more surprising effects of time-restricted feeding in mice eating a so-called healthy diet: increases in muscle mass and even endurance in some cases. Interested in trying out time-restricted feeding? Don’t let your data points go to waste! You can try out time-restricted feeding and have a real impact on human research! Commit to 14 weeks and download Dr. Panda’s mobile app to get started. Learn more at: mycircadianclock.org/participantRead More
Dr. Rhonda Patrick speaks with Ray Cronise, a former NASA material scientist and cofounder of zero gravity, a company that offers weightless parabolic flights to consumers and researchers. In this episode, coming at the tail end of a rather extreme 23-day water fast for Ray, we discuss, perhaps unsurprisingly, some of the benefits that are associated with fasting! Ray talks about shifting one’s perspective from looking at nutrition only through the lens of meeting day-to-day nutritional needs, and instead, also considering optimizing metabolism for longer-term effects as well, the importance of thinking about longevity in the context of functional healthspan, some of the similarities between the body’s physiological response to heat stress, cold stress, and exercise and so much more. Learn more about Ray Cronise by visiting his website at hypothermics.com (raycronise.com) or by saying hello on twitter: twitter.com/raycronise. Finally, Ray also has a book available for pre-order called “Our Broken Plate.”Read More