The power of the Ketogenic Diet with Dr. Dom D’Agostino

Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an assistant professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a senior research scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast.

Dom focuses on ketosis, ketones, and the ketogenic diet — so you can consider this a ketosis master class (especially if you combine both episodes, though this one does stand alone).

If you have an interest in these types of metabolic therapies, whether for performance enhancement, endurance, weight loss, or fighting cancer, diabetes, or any number of other maladies, you will find a gem within this episode.

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Time-Restricted Feeding and Its Effects on Obesity, Muscle Mass & Heart Health

Dr. Rhonda Patrick speaks with Dr. Satchin Panda, a professor at the Salk Institute for Biological Studies in La Jolla California. Satchin’s work deals specifically with the timing of food and it’s relationship with our biological clocks governed by circadian rhythm and also the circadian rhythm in general. In this video we discuss… The fascinating history of experimentation that ultimately elucidated the location for the region of the brain necessary for a properly timed sleep-wake cycles. The relationship between our body’s “master clock” and it’s many peripheral clocks. Why infants sleep so intermittently, instead of resting for a longer, sustained duration like healthy young adults… and why this sustained rest also goes haywire in the elderly. The fascinating work Dr. Panda took part in that lead to the discovery of a specialized light receptor in the eye that sets circadian rhythms and is known as melanopsin. The important relationship between the relatively light insensitive melanopsin, which requires around 1,000 lux of light to be fully activated, and its control of the circadian clock by means of activation of the suprachiasmatic nucleus and suppression of melatonin. The effects light exposure seems to have on next-day cortisol, a glucocorticoid hormone that regulates around 10-20% of the human protein-encoding genome. The clever experimental design by which Dr. Panda and his colleagues discovered that certain circadian rhythms, especially of the liver, are entrained by when we eat, instead of how much light we get. This underlines the fact that, when managing are circadian rhythm, both elements are important! One of the more surprising effects of time-restricted feeding in mice eating a so-called healthy diet: increases in muscle mass and even endurance in some cases. Interested in trying out time-restricted feeding? Don’t let your data points go to waste! You can try out time-restricted feeding and have a real impact on human research! Commit to 14 weeks and download Dr. Panda’s mobile app to get started. Learn more at: mycircadianclock.org/participant

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Joe Rogan Experience #773 – Dr. Rhonda Patrick

Dr. Rhonda Patrick returns with another nutrient dense discussion with Joe on cryotherapy/cold showers, diet, and exercise. As always this is not to be missed and we’ve noted all the most important parts for you, as it can be overwhelming in detail.

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Rich Roll Podcast: Dr. Rhonda Patrick

LONGEVITY, EPIGENETICS, MICROBIOME HEALTH & THE DIFFERENCE BETWEEN EATING FOR LONG-TERM WELLNESS VERSUS PERFORMANCE

This episode is a geeky deep dive into the hardcore science behind everything from telomeres and the mechanisms behind aging and longevity to the primacy of maintaining microbiome health; oxidative stress and the relationship between inflammation and chronic disease; epigenetics and genetic disposition versus expression; and of course nutrition – divining truth from myth, the impact of micronutrient inadequacies, focused supplementation and the difference between eating for optimal wellness versus performance.

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The Joe Rogan Experience: Dr. Rhonda Patrick

Rhonda and Joe go in depth on the damage from blows to the head during MMA, genetic risk factors for Alzheimer’s disease, the role of epigenetics and overall recommendations for how to eat, sleep, exercise and supplement.

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The Joe Rogan Experience: Rhonda Patrick (Part 1/2)

Full Episode, Podcast Score: 9/10 Microphones Sponsors: Squarespace (code: Joe), Legalzoom, Meundies, Onnit (code: Rogan) Find Rhonda Patrick at: Foundmyfitness.com, @foundmyfitness Part I Kombucha: Probiotic fermented drink (contains small levels of alcohol) Buy some / Make your own Water: You can die from drinking too much water (Radio contest, Frat hazing) Sauna Benefits: Rhonda goes in depth on her blog on Sauna … Continue reading The Joe Rogan Experience: Rhonda Patrick (Part 1/2)

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