LISTEN The guest on this episode of the podcast is Jason Nemer, co-founder of AcroYoga. What are the origins of AcroYoga? Jason had some sport acrobat experience, a mix between gymnastics and figure skating. Jenny had experience in therapeutic flying. AcroYoga is the combination of those two practices. It helps with flexibility and mobility. What … Continue reading Jason Nemer – Inside the Magic of AcroYogaRead More
Seth Godin (@thisissethsblog) is the author of 17 bestselling books that have been translated into more than 35 languages. He writes about the way ideas spread, marketing, strategic quitting, leadership, and — most of all — challenging the status quo in all areas. His books include Linchpin, Tribes, The Dip, Purple Cow, and What to Do When it’s Your Turn (and it’s Always Your Turn).
Seth has founded several companies, including Yoyodyne and Squidoo. His blog (which you can find by typing “Seth” into Google) is one of the most popular in the world. In 2013, Godin was inducted into the Direct Marketing Hall of Fame. Recently, Godin turned the book publishing world on its ear by launching a series of four books via Kickstarter. The campaign reached its goal in just three hours and became the most successful book project in Kickstarter history.
You’ll find pithy, actionable things that you can implement, such has how to keep track of the right things and how to create a narrative that serves you best. It’s very simple, but it’s a foundational skill and mindset.Read More
Tim visited the Googleplex — the Mountain View-based headquarters of Google — and had a public chat. I was interviewed and made sure that we covered some ground that has not been discussed before. There were questions such as:
What has been the most important Stoic teaching that I’ve come across?
How do I manage the many requests I receive?
What are the factors or elements that have led to the success of the podcast?
Where do I see myself in five years?
If I could pick three people — alive or dead — to be in my personal board of directors, who would they be?
How do I experiment with my dog training?
What are my recommendations for longevity?
How do I fight insomnia?
Dr. Ruth Patterson, a professor in the UC San Diego Department of Family Medicine and Public Health as well as Associate Director of Population Sciences and leader of the Cancer Prevention program at Moores Cancer Center at UC San Diego Health. If you enjoyed my last episode with Dr. Satchin Panda, I have good news! This will also be a great episode for you, since we talk about some similar ideas, but focus more on the human side of things, especially when it comes to time-restricted eating, since Dr. Patterson does primarily clinical research. In this 45-minute podcast, we talk about… The importance of time-restricted eating as a practical public health intervention, mostly for it’s ease of implementation, that may have a widespread impact on disease risk. Why you should probably make sure your time-restricted eating window occurs earlier in the day, rather than later. How the first 5% drop in weight loss can have disproportionately large effects on the metabolic factors associated with breast cancer risk when compared with subsequent weight loss. The association of longer fasting durations beginning earlier in the evening and improved sleep in humans, as well as spontaneous physical activity in their day-to-day lives. The relationship between metabolism and breast cancer risk. The effect of lifestyle factors, such as obesity, physical activity, what and even when you eat, whether or not you smoke tobacco… and how even modest changes, such as consuming food earlier in the day and only during an 11-hour window, can decrease breast cancer risk and recurrence by as much as 36%. The importance of starting your fast earlier in the evening, and how an earlier eating window has been shown to correlate to reductions in inflammatory markers.Read More
Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an assistant professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a senior research scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast.
Dom focuses on ketosis, ketones, and the ketogenic diet — so you can consider this a ketosis master class (especially if you combine both episodes, though this one does stand alone).
If you have an interest in these types of metabolic therapies, whether for performance enhancement, endurance, weight loss, or fighting cancer, diabetes, or any number of other maladies, you will find a gem within this episode.Read More
Dr. Rhonda Patrick speaks with Dr. Satchin Panda, a professor at the Salk Institute for Biological Studies in La Jolla California. Satchin’s work deals specifically with the timing of food and it’s relationship with our biological clocks governed by circadian rhythm and also the circadian rhythm in general. In this video we discuss… The fascinating history of experimentation that ultimately elucidated the location for the region of the brain necessary for a properly timed sleep-wake cycles. The relationship between our body’s “master clock” and it’s many peripheral clocks. Why infants sleep so intermittently, instead of resting for a longer, sustained duration like healthy young adults… and why this sustained rest also goes haywire in the elderly. The fascinating work Dr. Panda took part in that lead to the discovery of a specialized light receptor in the eye that sets circadian rhythms and is known as melanopsin. The important relationship between the relatively light insensitive melanopsin, which requires around 1,000 lux of light to be fully activated, and its control of the circadian clock by means of activation of the suprachiasmatic nucleus and suppression of melatonin. The effects light exposure seems to have on next-day cortisol, a glucocorticoid hormone that regulates around 10-20% of the human protein-encoding genome. The clever experimental design by which Dr. Panda and his colleagues discovered that certain circadian rhythms, especially of the liver, are entrained by when we eat, instead of how much light we get. This underlines the fact that, when managing are circadian rhythm, both elements are important! One of the more surprising effects of time-restricted feeding in mice eating a so-called healthy diet: increases in muscle mass and even endurance in some cases. Interested in trying out time-restricted feeding? Don’t let your data points go to waste! You can try out time-restricted feeding and have a real impact on human research! Commit to 14 weeks and download Dr. Panda’s mobile app to get started. Learn more at: mycircadianclock.org/participantRead More
Ryan Holiday (@RyanHoliday) is a strategist and writer. He dropped out of college at 19 to apprentice under Robert Greene, author of The 48 Laws of Power, and later served as the director of marketing for American Apparel. His company, Brass Check, has advised clients like Google, TASER, and Complex, as well as many prominent bestselling authors. Holiday has written four previous books, including The Obstacle Is the Way, which has been translated into 17 languages and has a cult following among NFL coaches, world-class athletes, TV personalities, political leaders, and others around the world. Ryan lives on a small ranch outside of Austin, Texas, and his latest book is Ego Is The Enemy.
Ryan and Tim cover a lot in this conversation, including:
Meltdowns and how Ryan handles them
Workaholics Anonymous — How it works, what worked for him, what didn’t
The tipping points for his last book, The Obstacle Is the Way
External versus internal obstacles
Sherman versus Grant leadership and “success”
Howard Hughes versus Elon Musk
Thinking of “first principles”
If you only have 5 minutes, listen to what Ryan believes is one of the biggest threats to your creativity.
Kevin is Senior Maverick at Wired Magazine, which he co-founded in 1993. He also co-founded the All Species Foundation, a non-profit aimed at cataloging and identifying every living species on earth. In his spare time, he writes bestselling books, co-founded The Rosetta Project, which is building an archive of all documented human languages, and serves on the board of The Long Now Foundation. As part of the last, he’s investigating how to revive and restore endangered or extinct species, including the Wooly Mammoth.
Kevin’s most recent project is The Inevitable: Understanding the 12 Technological Forces That Will Shape Our Future. The praise for the book is incredible, with Marc Andreessen saying it’s, “an automatic must-read.”Read More
Marc Andreessen (@pmarca) is a legendary figure in Silicon Valley — and worldwide. Even in the epicenter of tech, it’s hard to find a more fascinating icon.
Marc co-created the highly influential Mosaic Internet browser, the first widely used graphical web browser. He also co-founded Netscape, which later sold to AOL for $4.2 billion. Then he co-founded Loudcloud, which sold as Opsware to Hewlett Packard for $1.6 billion.
He’s considered one of the founding fathers of the modern Internet, right alongside pioneers like Tim Berners-Lee, who launched the Uniform Resource Locator (URL), Hypertext Transfer Protocol (HTTP), and early HTML standards.
This all makes him one of the few humans ever to create software categories used by more than a billion people. He’s also one of the few who’s established multiple billion-dollar companies.
Marc is now co-founder and general partner of venture capital firm Andreessen Horowitz, where he’s quickly become one of the most influential and dominant tech investors in the world.
In this interview, Tim digs into some fun things Marc has not discussed in many places, including:
His epic debate vs. Peter Thiel
Rules for investing
The future of bitcoin
Favorite books, documentaries, and movies
And much, much more
If you only have 5 minutes, here’s what Marc misses most about the mid-90s Internet (and what he’d like to bring back).
Please do say hi to Marc — he’s very active on Twitter at @pmarca.Read More
Dr. Rhonda Patrick speaks with Ray Cronise, a former NASA material scientist and cofounder of zero gravity, a company that offers weightless parabolic flights to consumers and researchers. In this episode, coming at the tail end of a rather extreme 23-day water fast for Ray, we discuss, perhaps unsurprisingly, some of the benefits that are associated with fasting! Ray talks about shifting one’s perspective from looking at nutrition only through the lens of meeting day-to-day nutritional needs, and instead, also considering optimizing metabolism for longer-term effects as well, the importance of thinking about longevity in the context of functional healthspan, some of the similarities between the body’s physiological response to heat stress, cold stress, and exercise and so much more. Learn more about Ray Cronise by visiting his website at hypothermics.com (raycronise.com) or by saying hello on twitter: twitter.com/raycronise. Finally, Ray also has a book available for pre-order called “Our Broken Plate.”Read More